Kevin Fitzgerald Selected Research

Myocardial Infarction

1/2016	RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.
4/2015	Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
4/2014	In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.
8/2010	From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.

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Kevin Fitzgerald Research Topics

Disease

7	Inflammation (Inflammations) 01/2016 - 08/2012
5	Anemia 01/2021 - 08/2012
4	Insulin Resistance 01/2023 - 02/2012
4	Myocardial Infarction 01/2016 - 08/2010
3	Liver Diseases (Liver Disease) 01/2023 - 05/2017
3	Primary Hyperoxaluria (Oxaluria, Primary) 01/2022 - 01/2016
3	Iron Overload 01/2021 - 04/2015
3	Thalassemia 01/2021 - 04/2015
3	Amyloidosis 01/2021 - 06/2016
3	beta-Thalassemia (Cooley's Anemia) 01/2021 - 04/2015
3	Acute Intermittent Porphyria (Porphyria, Acute) 01/2019 - 05/2014
3	Obesity 11/2017 - 02/2012
2	Rare Diseases (Rare Disease) 02/2024 - 01/2017
2	Non-alcoholic Fatty Liver Disease 01/2023 - 01/2023
2	Hypercholesterolemia 01/2022 - 08/2008
2	Disease Progression 01/2021 - 03/2013
2	Polyneuropathies (Polyneuropathy) 01/2021 - 01/2021
2	Neoplasms (Cancer) 06/2020 - 03/2012
2	Hepatocellular Carcinoma (Hepatoma) 06/2020 - 03/2012
2	Hyperinsulinism (Hyperinsulinemia) 01/2020 - 02/2012
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 03/2014
2	Body Weight (Weight, Body) 01/2019 - 08/2013
2	Fatty Liver 11/2017 - 02/2012
2	Hypertriglyceridemia 08/2017 - 02/2012
2	Heart Failure 09/2016 - 04/2014
2	Renal Insufficiency (Renal Failure) 01/2016 - 08/2012
2	Hepatic Porphyrias (Hepatic Porphyria) 11/2015 - 05/2014
2	Atherosclerotic Plaque (Atheroma) 04/2015 - 03/2013
2	Infarction (Infarctions) 04/2014 - 05/2013
1	Chronic Disease (Chronic Diseases) 02/2024
1	Alzheimer Disease (Alzheimer's Disease) 10/2022
1	Abdominal Obesity 01/2022
1	Hemochromatosis (Bronze Diabetes) 01/2021
1	Erythropoietic Porphyria (Congenital Erythropoietic Porphyria) 01/2020
1	AIDS-Related Complex (ARC) 01/2020
1	Multiple Myeloma 01/2020
1	Iron Deficiencies 01/2020
1	Hypoglycemia (Reactive Hypoglycemia) 01/2020
1	Congenital Hyperinsulinism 01/2020
1	Erythropoietic Protoporphyria 01/2020
1	Arthrogryposis renal dysfunction cholestasis syndrome 01/2020
1	Short Bowel Syndrome 11/2019
1	Myasthenia Gravis 06/2019

Drug/Important Bio-Agent (IBA)

14	Small Interfering RNA (siRNA)IBA 10/2022 - 05/2013
5	HepcidinsIBA 01/2021 - 08/2012
4	FructoseIBA 01/2023 - 11/2017
4	Proteins (Proteins, Gene)FDA Link 10/2022 - 03/2012
4	IronIBA 01/2021 - 04/2015
4	Prealbumin (Transthyretin)IBA 01/2021 - 08/2013
3	Triglycerides (Triacylglycerol)IBA 01/2023 - 05/2012
3	Amyloid (Amyloid Fibrils)IBA 10/2022 - 08/2013
3	GlobinsIBA 01/2021 - 04/2015
3	Messenger RNA (mRNA)IBA 01/2020 - 06/2015
3	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 11/2017
3	Heme (Haem)IBA 01/2019 - 05/2014
3	OxalatesIBA 01/2017 - 01/2016
3	Transcription Factors (Transcription Factor)IBA 04/2014 - 02/2012
3	LDL CholesterolIBA 01/2014 - 08/2010
2	AcetylgalactosamineIBA 01/2022 - 06/2019
2	Acute Hepatic PorphyriaIBA 01/2022 - 05/2014
2	givosiranIBA 01/2022 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2013
2	patisiranIBA 01/2021 - 08/2013
2	Hormones (Hormone)IBA 01/2021 - 04/2015
2	EnzymesIBA 11/2017 - 01/2017
2	Sterol Regulatory Element Binding Protein 1IBA 08/2017 - 02/2012
2	LipidsIBA 05/2017 - 02/2012
2	Calcium OxalateIBA 01/2017 - 01/2016
2	glycollate oxidaseIBA 01/2017 - 01/2016
2	Chemokine ReceptorsIBA 06/2015 - 05/2013
2	Apolipoproteins E (ApoE)IBA 04/2015 - 05/2013
1	OligonucleotidesIBA 01/2022
1	LigandsIBA 01/2022
1	Antisense OligonucleotidesIBA 01/2022
1	lumasiranIBA 01/2022
1	ALN-PCSIBA 01/2022
1	Activins (Activin)IBA 01/2022
1	ProteomeIBA 01/2021
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2021
1	QuinolonesIBA 06/2020
1	Phosphotransferases (Kinase)IBA 06/2020
1	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 01/2020
1	LactamsIBA 01/2020
1	Ferrochelatase (Heme Synthetase)IBA 01/2020
1	Glucagon (Glukagon)FDA Link 01/2020
1	CateninsIBA 01/2020
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 01/2020
1	Insulin (Novolin)FDA Link 01/2020
1	protoporphyrin IXIBA 01/2020
1	Surface Antigens (Surface Antigen)IBA 01/2020
1	AntibodiesIBA 01/2020
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	Dietary SugarsIBA 10/2019
1	Complement System Proteins (Complement)IBA 06/2019

Therapy/Procedure

11	Therapeutics 01/2022 - 03/2013
10	RNAi Therapeutics 02/2024 - 08/2008
3	Parenteral Nutrition 11/2019 - 05/2017
2	Ligation 09/2016 - 04/2014
1	Injections 01/2019